No. PEEK and PTFE can both resist many chemicals, but they behave differently in stiffness, friction, deformation, temperature response and fitting interaction. Victrex describes PEEK as having high strength, stiffness, creep resistance and dimensional stability; this is why a PEEK tube may route with more force and transmit more stress than a soft fluoropolymer tube. A substitution review should compare ID clearance, bend radius, insertion force, vibration, chemicals, temperature, pressure or electrical duty and the connection design. Test the assembled component before changing materials